- Rapid cognitive improvement in Alzheimer’s disease following perispinal etanercept administration. Edward Tobinick MD, Hyman Gross MD. Journal of Neuroinflammation. 2008 Jan 9;5:2.
- Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer’s disease. Edward Tobinick MD, H. Gross MD. BMC Neurology. 2008 Jul 21;8:27.
- Perispinal etanercept for treatment of Alzheimer’s disease. Edward Tobinick MD. Current Alzheimer Research. 2007 Dec;4(5):550-2.
- Perispinal etanercept: potential as an Alzheimer therapeutic.Griffin WS. J Neuroinflammation. 2008 Jan 10;5:3. (FULL-TEXT HERE).
- Tumour necrosis factor modulation for treatment of Alzheimer’s disease: rationale and current evidence. Edward Tobinick MD. CNS Drugs. 2009 Sep 1;23(9):713-25.
- Perispinal etanercept for neuroinflammatory disorders. Edward Tobinick MD. Drug Discovery Today. 2009 Feb;14(3-4):168-77.
- Perispinal etanercept: a new therapeutic paradigm in neurology. Edward Tobinick MD. Expert Review of Neurotherapeutics. 2010 Jun;10(6):985-1002.
- Deciphering the physiology underlying the rapid clinical effects of perispinal etanercept in Alzheimer’s disease. Edward Tobinick MD. Current Alzheimer Research. 2012 Jan 1; 9(1):99-109. (Free full-text PDF available here).
- Targeting Tumor Necrosis Factor Alpha for Alzheimer’s Disease. Decourt B, Lahiri DK, Sabbagh MN. Curr Alzheimer Res. 2017;14(4):412-425. (Decourt Targeting TNFa for Alzheimer’s Disease). (Free full-text PDF available here).
- Therapeutic Potential of TNF-α Inhibition for Alzheimer’s Disease Prevention. Torres-Acosta N, O’Keefe JH, O’Keefe EL, Isaacson R, Small G. J Alzheimers Dis. 2020;78(2):619-626. (Free full-text PDF available here).
- Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer’s disease in patients with rheumatoid arthritis and psoriasis. Zhou M, Xu R, Kaelber DC, Gurney ME. PLoS One. 2020 Mar 23;15(3):e0229819. (Free full-text PDF available here).
- Action of anti-TNF-α drugs on the progression of Alzheimer’s disease: A case report. Camargo CHF, Justus FF, Retzlaff G, Blood MRY, Schafranski MD. Dement Neuropsychol. 2015 Apr-Jun;9(2):196-200. (Free full-text PDF available here).
- TNF alpha inhibitors in Alzheimer’s disease: A systematic review. Ekert JO, Gould RL, Reynolds G, Howard RJ. Int J Geriatr Psychiatry. 2018 May;33(5):688-694.
- Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Alzheimers Dement. 2022 Jun;18(6):1248-1259. (Free full-text PDF available here).
- Targeting TNF: a therapeutic strategy for Alzheimer’s disease. Cheng X, Shen Y, Li R. Drug Discov Today. 2014 Nov;19(11):1822-1827
- Treatment for Rheumatoid Arthritis and Risk of Alzheimer’s Disease: A Nested Case-Control Analysis. Chou RC, Kane M, Ghimire S, Gautam S, Gui J. CNS Drugs. 2016 Nov;30(11):1111-1120. (Free full-text PDF available here).
- Neuroinflammation in Alzheimer’s Disease. Onyango IG, Jauregui GV, Čarná M, Bennett JP Jr, Stokin GB. Biomedicines. 2021 May 7;9(5):524. (Free full-text PDF available here).
- Association between disease-modifying antirheumatic drugs for rheumatoid arthritis and risk of incident dementia: a systematic review with meta-analysis. Xie W, Hou Y, Xiao S, Zhang X, Zhang Z. RMD Open. 2024;10:e004016. (Free full-text PDF available here).
- Impact of TNF inhibitors on inflammation-associated cognitive dysfunction in patients with rheumatoid arthritis: a prospective analysis. Mena-Vázquez N, Ortiz-Márquez F, Ramirez-García T, Gillis-Onieva C, Cabezudo-García P, García-Studer A, Mucientes A, Lisbona-Montañez JM, Borregón-Garrido P, Ruiz-Limón P, Manrique-Arija S, Cano-García L, Serrano-Castro PJ, Fernández-Nebro A. Front Med (Lausanne). 2025 Apr 11;12:1561140. (Free full-text PDF available here).
- Effect of TNF-α blockers on reducing the risk of dementia in rheumatoid arthritis: a nationwide cohort study. Chen LF, Lin TM, Chang YS, Hsu HC, Shen YC, Lin SH, Chen WS, Hu LF, Kuo PI, Kuo TT, Chen SC, Chen JH, Lien YK, Chang CC. Clin Exp Rheumatol. 2025 May;43(5):931-938.
- Dementia Risk in Psoriasis Patients Treated with Biologics: A Propensity Score-matched Population-based Cohort Study. Barak Levitt JA, Ziv M. Acta Derm Venereol. 2025 May 13;105:adv43243. (Free full-text PDF available here).
- Association of Tumor Necrosis Factor-α Inhibitors with Incident Dementia: Analysis Based on Population-Based Cohort Studies. Berger S, Moseholm KF, Hegelund ER, Tesch F, Nguyen MCS, Mortensen LH, Jensen MK, Schmitt J, Mukamal KJ. Drugs Aging. 2024 May;41(5):423-430. (Free full-text PDF available here).
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